Subject Descriptions - Subject Information

Calendar: 2017 Undergraduate
Faculty: Faculty of Science, Medicine and Health
Department: School of Biological Sciences

Subject Information
Subject Code CHEM320
Subject Name Bioinformatics: From Genome to Structure
Credit Points 8
Pre-Requisites BIOL213
Co-Requisites Nil
Restrictions Nil
Equivalence Not to count for credit with BIOL318
Assessment Practical work 35%; Quiz (multiple choice) 10%; Final written examination 55%.
General Subject Yes.

Subject Description
This subject will be divided into three strands of approximately equal length: (i) Bioinformatics, (ii) Biological macromolecules (proteins and nucleic acids) - structure and function, and (iii) Proteomics. In the practical classes, bioinformatics will be explored in computer-based tutorials and practicals. Databases for nucleic acid and protein sequences, structures and other parameters of biological molecules, plus linkages to the scientific literature, will be used to extract information and to compare and analyse these data. Proteomics and protein and nucleic acid structure will also be investigated via computer-based practicals. In the laboratory, the structure/function aspects of the protein, lysozyme, will be analysed.

Subject Learning Outcomes
On successful completion of this subject, students will be able to:
1. Appreciate the significance and scope of bioinformatics in biology and biotechnology;
2. Access and utilise a range of databases with computer-based applications to discover information about genes, their products and biological effects;
3. Contrast how biological macromolecules interact and regulate chemical reactions in biology;
4. Understand the significance and scope of bioinformatics in biotechnology, pharmaceuticals and medicine;
5. Be competent in accessing and utilising biological databases with a range of computer-based applications;
6. Understand the methods used to isolate and identify proteins (proteomics).